| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Vitamins | 15 | Vitamin B12-Isolated folate supplementation worsening neuropathy -animal products(asked thrice) ,Vitamin D Def, Niacin deficiency-diet rich in maize (asked twice) ,Vitamin B6, Vitamin K-gamma glutamyl carboxylase activation, Vitamin B3-image of cassals necklace,Viatmin B1 , Vitamin C deficiency-decreased collagen, Biotin deficiency, Vitamin B2 deficinecy-Glutathione reductase, Vitamin A deficiency-conjunctival xerosis, Vitamin B9 | High | 3 hrs including all |
| Minerals | 2 | Zinc deficiency,copper deficiency | Moderate | same as above |
| Chronic alcoholism | 1 | With gouty arthritis -increased urate and lactate levels | low | same as above |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Glycogen storage disorders | 4 | Pompes-clinical presentation(2) ,McArdles-Myophosphorylase deficiency, Glycogen storage disorder - Type 0 | High | 1 hour |
| Cycles - Insulin:Glucagon ratio | 2 | Glucose 6 phosphatase , Hormone sensitive lipase activation in low insulin glucagon ratio | Moderate | 1 hour including rest |
| Galactosemia | 1 | Gal PUT deficiency | Low | same as above |
| HMP pathway | 1 | Primaquine induced hemolytic anemia | Low | same as above |
| GAGs in corenal transparency | 1 | Keratan sulfate | Low | same as above |
| Hepatic glycogenolysis | 1 | Responsible for fasting blood sugar | Low | same as above |
| PDH complex | 1 | cellular respiration | Low | same as above |
| Cellulose | 1 | Absorbs least water | Low | same as above |
| Glucose transporters | 1 | Insulin sensitive-GLUT 4 | Low | same as above |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Lysosomal storage disorder | 6 | Gauchers disease-crumpled tissue paer appearance ,glucocerbroside deficiency (5) , Tay Sachs disease-cherry red spot | High | 2 hours including all |
| Familial Hypercholesterolemia | 3 | LDL receptor defect, Achilles tendon xanthoma | High | same as above |
| Apolipoprotein CII | 1 | Familial Chylomicronemia syndrome | Low | same as above |
| Carnitine deficiency | 1 | Muscle biopsy shows fat vacuoles | Low | same as above |
| Transportation of fatty acid through inner mitochondrial membrane | 1 | Carnitine | Low | same as above |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Alkaptonuria | 3 | Homogentisic acid 1,2-dioxygenase deficiency , Urine turns black on standing | High | 1 .5 hour including all |
| Homocystinuria | 2 | Cysteine supplementation,Cystathione Beta synthase which needs Vitamin B6 as cofactor | High | same as above |
| Phenylketonuria | 1 | Dihydrobiopterene reductase deficiency | Low | same as above |
| UV absorbance of protein | 1 | Replacing alanine by Tryptopahn increases UV absorbance of protein at 280 nm | Low | same as above |
| Protein structure | 1 | Tertiary sytructire in 3 dimensional | Low | same as above |
| NO synthesis | 1 | From L arginine | Low | same as above |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Autosomal recessive inheritance | 1 | Cystic Fibrosis -AR | Moderate | 1.5 hr including all |
| Non sense mutation | 1 | Single mutation in nucleotide base pair leading to a termination codon | Moderate | same as above |
| DNA packing | 1 | Histone responsible for DNA packing | Moderate | same as above |
| Mismatch repair | 1 | HNPCC | Moderate | same as above |
| Proteasome | 1 | Function in protein degradation | Moderate | same as above |
| RNA editing | 1 | in syntheis of apolipoprotein B48 | Moderate | same as above |
| Chargaff rule | 1 | Percentage of nucelotides in DNA - THYMINE 28% , CYTOSINE 22% | Moderate | same as above |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| ETC | 1 | ETC | Moderate | 30 minutes including all |
| Complex IV inhibitors | 1 | Cyanide is inhibitor | Moderate | same as above |
| Mitochondrial Respiration | 1 | Blocked by oligomycin | Moderate | same as above |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Lesch Nyhan Syndrome | 1 | Clinical history | low | 15 minutes |
| Topic Name | Times Repeated | PYQ Asked | Priority | Study Duration |
|---|---|---|---|---|
| Inhibition | 2 | Competitive- increasing substrate will overcome inhibition, graph and Non competitive | Moderate | 15 minutes |
| Van Den Berg reaction | 1 | Obstructive jaundice - direct positive | Low | 15 minutes |
| Lead poisoning | 1 | Urinary coproporphyrin positive | Low | 15 minutes |