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pharmacology

GENERAL PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Pharmacokinetics and Pharmacodynamics 4 Dose respone curve ,Drug potency,Non competitive inhibition, Digoxin pharmacokinetics , Dosing rate of drug formula High 0.5
Enzyme inducers and inhibitors 2 Erythromycin inhibiting effect of Theophylline Moderate 0.25
Drug prescription 1 Alprazolam Low 0.25
Drug dosing 1 Loading dose dependent on volume of distribution Low 0.25

ANTIMICROBIALS

Topic Name Times Repeated PYQ Asked Priority Study Duration
Anti TB 5 Isoniazid (asked twice) ,Inclusion criteria for Bedaquiline ,Rifampicin-,MOA induces OCP metabolism, Pyridoxine supplementation with Isoniazid High 1
Antimalarials 3 Chloroquine-side effect-gets deposited in cornea (asked twice) High 0.5
Antifungal 3 Clotrimazole- treatment of oral thrush, Amphotercin B-treatment of mucor, Azoles- Voriconazole not useful in mucormycosis High 0.5
Antimicrobials 3 Floroquinolones-Pefloxacin contraindicated in liver disease, Mechanism of action, Mechanism of resistnace in Bera-lactams,Clarithromycin can cause digoxin toxicity High 1
Antiparasitic 1 Metronidazole- Disulfiram reaction with alcohol Low 0.5
AntiHIV 1 Drug interaction with Rifampicin Low 0.5

CVS PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Antihypertensives 7 Bisoprolol (imoproves cardiac mortality ), Clonidine - rebound hypertension (asked twice),Omapratilat-Mechanism of action,ARB-Losartan - Drug induced angioedema, Drugs contraindicated in pregnancy High 1
Antiarrhythmic 6 Amiodarone-adverse effects (asked thrice),Digoxin toxicity - Digifab(asked twice),Adenosine High 1
Antianginal 2 Ranolazine-MOA Moderate 0.25
Drugs for Dyslipidemia 2 Nicotinamide adverse effects,Evolocumab-MOA Moderate 0.25

CNS PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Antiparkinsons 3 Trihexiphenidyl/Benzhexol- Drug induced dyskinesia (asked twice) , Selegiline High 0.75
Antipsychotic and Antidepressant 3 Lithium-toxicity, SNRI - Reboxatine High 0.75
Benzodiazepine 1 Alprazolam prescription in the night Low 0.25

ANS PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Antimuscarinic 7 Atropine-OP poisoning treatment (asked thrice ),Dhatura poisoning , Tolterodine, Botulinum toxin High 1.5
Anti adrenergic 1 Tamsulosin Low 0.25
Epinephrine 1 Shifts potassium into cells Low 0.25
Methylphenidate 1 used in treatment of ADHD Low 0.25
Reversal of Anaesthesia/ Muscle relaxant 1 Neostigmine for revrsal of Vecuronium in renal failure Low 0.25
Muscarinic 1 Bethanechol for post operative urinary retention Low 0.25

ENDOCRINE PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
GH analogue , Inhibition 3 Pegvisomant-indication, Tesamorelin-HIV associated Lipodystrophy, Octreotide-GH producing tumor-Acromegaly treatment High 0.75
OHA 2 Metformin (asked twice) Moderate 1
Osteoporosis 2 Bisphosphanates Moderate 0.75

AUTACOIDS AND PAIN

Topic Name Times Repeated PYQ Asked Priority Study Duration
NSAIDs 5 Aspirin-,Mechanism of action ,Samters triad, Toxicity(asked thrice ) ,Indomethacin-premature closure of PDA ( asked twice ) High 1
Opioids and withdrawal 2 Buprenorphine- opiod withdrawal , Morphine-aggravates biliary colic Moderate 0.5
Prostaglandins 2 Carboprost-CI in treatment of PPH with Asthma , Latanoprost-Antiglaucoma Moderate 0.5
Antispasmodic 1 Dicyclomine Low 0.25
Analgesic in CKD 1 Acetaminophen can be used Low 0.25

HAEMATOLOGY AND ANTICANCER DRUGS

Topic Name Times Repeated PYQ Asked Priority Study Duration
Anticoagulants and Fibrinolytics 5 warfarin-Purple toe syndrome (asked twice ) , Vitamin K-deficiency causing bleeding ( asked twice ), Tissue plasminogen activator- MOA,LMWH - pregnant with DVT High 1.5
Methotrexate 2 Reduced synthesis of TMP, competitive inhibitor of DHFR Moderate 0.5
Bortezomib 1 Increase risk of zoster Low 0.25
Operlvekin 1 Treatment of chemotherapy induced thrombocytopenia Low 0.25
Hemostatics 1 Aminocaproic acid- Mechanism of action Low 0.25
Antimetabolites 1 6-Mercaptopurine Low 0.25

GIT PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Antiemetics 5 Prokinetic agents , Metoclopramide-side effects , Promethazine- treatment of motion sickness ( asked twice ),Aprepitant-MOA High 0.5
Antidiarrheals 1 Atropine + Diphenoxylate to reduce addiction potential Low 0.25

RS PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Anti asthmatics 2 Inhaled steroids, Theophylline-Diuresis, MOA through Adenosine receptor Moderate 0.5
Pulmonary fibrosis 1 Drugs causing - Methysergide, Bleomycin , Nitrofurantoin Low 0.25

RENAL PHARMACOLOGY

Topic Name Times Repeated PYQ Asked Priority Study Duration
Diuretics 3 Thiazides- contraindicated in gout , preferred antihypertensive with renal colic(asked twice ) , Mannitol High 0.75
Gout 3 Drugs causing gout ,Peglotocase, Allopurinol Moderate 0.75
Tolvaptan 1 Mechanism of action Low 0.25

MISCELLANEOUS

Topic Name Times Repeated PYQ Asked Priority Study Duration
Toclizumab 1 Mechanism of action Low 0.25
Iron posoning 1 British AntiLewisite contraindicated Low 0.25